Electrophilic oligodeoxynucleotide synthesis using dM-Dmoc for amino protection

• Shahien Shahsavari,
• Dhananjani N. A. M. Eriyagama,
• Bhaskar Halami,
• Vagarshak Begoyan,
• Marina Tanasova,
• Jinsen Chen and
• Shiyue Fang

Beilstein J. Org. Chem. 2019, 15, 1116–1128, doi:10.3762/bjoc.15.108

• protections, which contained a tertiary butyl carbamate moiety, were not completely stable under the acidic conditions needed for de-tritylation in each synthetic cycle. Once the protection was lost, in the coupling step, incoming phosphoramidites would react with the free amino groups, and branched ODNs

An expedient and new synthesis of pyrrolo[1,2-b]pyridazine derivatives

• Rajeshwar Reddy Sagyam,
• Ravinder Buchikonda,
• Jaya Prakash Pitta,
• Himabindu Vurimidi,
• Pratap Reddy Padi and
• Mahesh Reddy Ghanta

Beilstein J. Org. Chem. 2009, 5, No. 66, doi:10.3762/bjoc.5.66

• ; tertiary butyl carbamate; tertiary butyl carbazate; α,β-unsaturated ketone; Introduction Pyrrolopyridazine derivatives have various biological applications [1][2][3][4][5][6][7][8], and their fluorescent properties have been investigated for potential use in sensors, lasers, and semiconductor devices [9